During a period of 5 years, 74 female and 27 male patients with an average age of 63.3 years underwent a total of 117 operations for the management of impending ( n=41) or already existing ( n=76) pathologic fractures due to osseous metastases. The average stay in hospital was 17.8 days, and the average postoperative survival 15.8 months. The patients whose limbs were stabilized as a preventive measure were discharged 1.5 days earlier and survived surgery 5.9 months longer than the patients with pathologic fractures.
The large percentage of female patients is due to the predominant role of mammary cancer (50%) and the comparatively long survival of patients after a primary diagnosis of this type of carcinoma. The other diagnoses involved were (in order of frequency): bronchial carcinoma (11%), hypernephroma (8%) and non-Hodgkin's lymphoma (8%). The metastases were mainly located at the proximal end or shaft of the femur (59.8%) and in the humerus (18.8%) so that in the majority of cases it was possible to implant weight-bearing prostheses or at least achieve enough stability to allow non-weight-bearing physiotherapy and thus early remobilization. The rate of systemic complications (excluding fatalities) was 14.5%. Local complications in the operated area occurred in 24.8% of cases. As a result, revision surgery was necessary in 10 cases (8.5%), and the fatality rate in hospital (6 weeks) was 7.9%. In view of the advanced stage of the disease in most of the patients, some of them with polypathia, we see these results as a basis for the generous indication for preventive stabilization of osseous metastases. Except in some cases, the primary intention of this therapy is not to cure the disease or prolong life but to improve the quality of life remaining for these patients while keeping their stay in hospital as short as possible and the rate of complications at an acceptable level.
Erschienen: Wiley Online Library – 2016
Autoren: Alexander Katzer, Michael Hahn, Björn Busse, Mathias Procop, Jozef Zustin, Michael Amling
Erschienen: ACTA ORTHOPEDICA – November 2008
Autoren: Wolfram Steens, Jochen F. Loehr, Joachim Wodtke, Alexander Katzer
Erschienen: Journal of Biomedical Materials Research Part A – November 2008
Autoren: B. Busse, M. Hahn, M. Niecke, B. Jobke, K. Püschel, G. Delling, A. Katze
Erschienen: Journal of Orthopaedics and Traumatology - December 2007
Autoren: A. Katzer, A. Ince, M. Hahn, M.M. Morlock, W. Steens
Erschienen: The Journal of Bone & Joint Surgery – November 2006
Autoren: J. Gille, A. Ince, O. González, A. Katzer, J. F. Loehr
Weiterlesen … Single-stage revision of peri-prosthetic infection following total elbow replacement
Erschienen: ACTA ORTHOPEDICA – November 2008
Autoren: Wolfram Steens, Goetz von Foerster, Alexander Katzer
Erschienen: Orthopädische Praxis – 41 / 2005
Autoren: A. Katzer, J. Gille, K. Seemann
Erschienen: The Journal of Bone & Joint Surgery - 2005
Autoren: A. Ince, K. Seemann, L. Frommelt, A. Katzer, J.F. Loehr
Weiterlesen … Onestage exchange shoulder arthroplasty for peri-prosthetic infection
Erschienen: Clinical Infectious Diseases – Januar 2005
Autoren: A. Ince, J. Rupp, L. Frommelt, A. Katzer, J. Gille, J.F. Löhr
Erschienen: Orthopedics – Dezember 2004
Autoren: Alexander Katzer, Frank Sickelmann, Klaus Seemann, Jochen F. Löhr
Weiterlesen … Two-Year Results After Exchange Shoulder Arthroplasty Using Inverse Implants
Erschienen: Biomaterials – Mai 2002
Autoren: A. Katzer, H. Marquardt, J. Westendorf, J.V. Wening, G. von Foerster
Weiterlesen … Polyetheretherketone - Cytotoxicity and mutagenicity in vitro
Autoren: Alexander Katzer, Wolf-Peter Niedermauntel, Corinna Haack, Jörg Rump
Weiterlesen … Mittelfristige Ergebnisse mit der CFP-Prothese
Autoren: R. Souffrant, R. Schubert, W. Steens, A. Katzer, W. Mittelmeier, R. Bader
Erschienen: In vivo - Juli 2011
Autoren: Andreas Burkandt, Alexander Katzer, Karlheinz Thaler, Volker von Baehr, Reinhard E. Friedrich, Wolfgang Rüther, Michael Amling, Jozef Zustin
Weiterlesen … Proliferation of the synovial lining cell layer in suggested metal hypersensitivity
Erschienen: Biology of Metals – Mai 2008
Autoren: Wolfram Steens, Alexander Katzer
Weiterlesen … Severe cobalt poisoning in endoprosthetic replacement of the hip
Autoren: Alexander Katzer, Michel Hahn, M. Niecke, B. Jobke, K. Püschel, G. Delling, Björn Busse
Erschienen: Der Orthopäde – September 2006
Autoren: W. Steens, J. F. Loehr, G. von Foerster, A. Katzer
Weiterlesen … Chronic cobalt poisoning in endoprosthetic replacement
Erschienen: Der Orthopäde – September 2006
Autoren: W. Steens, J. F. Loehr, G. von Foerster, A. Katzer
Weiterlesen … Chronische Kobaltvergiftung in der Endoprothetik
Erschienen: The Journal of Arthroplasty – Juli 2006
Autoren: Alexander Katzer, Akif Ince, Joachim Wodtke, Jochen F. Loehr
Weiterlesen … Component Exchange in Treatment of Periprosthetic Femoral Fractures
Erschienen: European Journal of Trauma – April 2006
Autoren: Alexander Katzer, Wolfram Steens, Akif Ince
Erschienen: Journal of Orthopaedics and Traumatology – Juli 2004
Autoren: A. Ince, A. Katzer, J. Gille, J. F. Löhr, P. Moubayed
Erschienen: Hüftchirurgie in der Praxis – Dezember 2005
Autoren: J.F. Löhr, A. Katzer
Erschienen: Toxicology – September 2003
Autoren: A Katzer, S. Hockertz, G. H. Buchhorn, J. F. Loehr
Weiterlesen … In vitro toxicity and mutagenicity of CoCrMo and Ti6Al wear particles
Erschienen: Toxicology – September 2003
Autoren: A Katzer, S. Hockertz, G. H. Buchhorn, J. F. Loehr
Weiterlesen … In-vitro-Toxizität und Mutagenität von CoCrMo und TiAl-Abriebpartikeln
Erschienen: Der Orthopäde 09/2003
Autoren: J F Loehr, N. Gschwend, B. R. Simmen, A. Katzer
Erschienen: Der Orthopäde – Juli 2003
Autoren: J. F. Loehr, N. Gschwend, B. R. Simmen, A. Katzer
Autoren: Alexander Katzer, Akif Ince, Joachim Wodtke, Jochen F. Loehr
Weiterlesen … Komponentenwechsel bei periprothetischen Femurfrakturen
Erschienen: Journal of Orthopaedics and Traumatology – März 2003
Autoren: A. Katzer, H.C. Moeller, J.V. Wening, K.H. Jungbluth
Erschienen: Journal of Orthopaedics and Traumatology – Januar 2003
Autoren: A. Katzer, J.F. Lœhr
Weiterlesen … Early loosening of hip replacements: Causes, course and diagnosis
Erschienen: Aktuelle Traumatologie – August 2002
Autoren: A. Katzer, R. Sellckau, W. Siemsen, G. von Foerster
Weiterlesen … Rotating Knee Total Prosthesis ENDO-Modell - A functional analysis
Erschienen: Archives of Orthopaedic and Trauma Surgery - Juli 2002
Autoren: Alexander Katzer, Norbert M. Meenen, Frederike Grabbe, Johannes Maria Rueger
Erschienen: Journal of Orthopaedics and Traumatology – Januar 2002
Autor: Alexander Katzer